Welcome to the Harvard OTD Collaborative Opportunity Finder, a new tool that will assist those working in the life science industry to explore commercial partnerships, such as industry sponsored research, with the talented research faculty at Harvard.
Search for collaborative research opportunities available through Harvard's Office of Technology Development:
Study neuronal circuits in the mouse involved with pheromone signaling in terms of their development, processing, architecture, and function; investigate the role genomic imprinting role in mammalian brain development, function, and disease.
Dr. Richard Losick’s laboratory investigates the mechanisms of bacterial biofilm formation and disassembly and applies this knowledge to antimicrobial development, clean water supply, protein and small molecule production, and other commercial opportunities; the lab also carries out studies of cell division and sporulation of Bacillus subtilis.
Study synaptic plasticity in the rodent brain to understand compensation mechanisms, how neurons maintain stable function during perturbations; understand the function of neuronal circuits in the rodent olfactory system and how they mediate the sense of smell.
Investigating genome-wide transcriptional dynamics, and studying multi-drug resistance in bacteria.
Chronic sleep disturbance is a problem for a significant number of Americans, but the mechanisms that control sleep and wakefulness are largely unknown. The Schier lab is using zebrafish to investigate the genes and circuits that regulate sleeping. Zebrafish are a useful model system because both genetic and imaging approaches can be easily combined to study complex behaviors in a vertebrate system. Importantly, zebrafish have behaviors that distinguish awake fish from sleeping fish …
Investigate the molecular mechanisms underlying the ability of bacterial cells to discriminate self from non-self; study the bacterium Proteus mirabilis, a Gram-negative opportunistic pathogen that forms biofilms and causes urinary tract infections and kidney stones in patients.
In order to better understand the way information about the world is stored in the brain and what form that information takes we generate neuronal maps, connectomes, and investigate the mechanisms that underlie synaptic competition between neurons that innervate the same target. We also directly visualize synaptic rearrangements in living transgenic animals using modern optical imaging techniques and new labeling methods. The developmental changes in wiring mechanisms may be a means by which …
Synapses are the main information processing sites in the brain. Defects in their function underlie many neurological and behavioral disorders, and there is increasing evidence that many of these defects arise from aberrant development. The Sanes lab seeks to understand how neurons form synaptic connections during development, and how in some cases they can re-form following injury. These studies will shed light on disease and aging related neurological dysfunctions, and provide a broad …