Investigators
Please locate individual investigators by clicking on the appropriate letter tab. Investigators can also be identified by Research Category, Sub-Category, or Keyword. Please note that research descriptions are not available for every HMS faculty member.
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Bean, Bruce
ProfessorNeuronal electrical signaling, ion channels, pacemaking, and neuropharmacology
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Beckwith, Jonathan
ProfessorStudy cellular processes in bacteria: protein folding, reduction and formation of protein disulfide bonds, membrane protein dynamics
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Blenis, John
ProfessorSignal transduction: nutrient and energy sensing; disease; mTOR; PI3-kinase; Ras
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Brugge, Joan
Professor and ChairEpithelial cell biology; mechanisms of breast and ovarian cancer development
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Chou, James
Associate ProfessorNMR spectroscopy and membrane protein structure; viral ion channels; antiviral compounds
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Clardy, Jon
ProfessorIsolation and characterization of small molecule natural products; high-throughput screening for novel therapeutics
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Dorf, Martin
ProfessorMolecular signaling in inflammation: TNF; cytokine; autoimmune disease; T-cell
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Farzan, Michael
Associate ProfessorVIRAL ENTRY AND ANTI-VIRAL STRATEGIES Viral Receptors; HIV Therapy; Dengue Virus; SARS; Ebola Virus
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Finley, Daniel
ProfessorUbiquitin-dependent protein degradation and the proteasome: mechanisms and coordination; architecture; role in disease
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Fontana, Walter
ProfessorInformation biology: principles, limits, and evolution of information processing in molecular systems
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Gunawardena, Jeremy
Senior LecturerExperimental and theoretical analysis of signal transduction: EGF signaling, drug efficacy, phosphorylation states, microfluidics, formalized biology language
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Haigis, Marcia
Assistant ProfessorMitochondrial dysfunction in aging and disease: bioenergetics, metabolomics, and cell stress
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Halperin, Jose
Associate ProfessorTargeting protein translation for anticancer therapies; CD59 and diabetes
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Harlow, Ed
Professor and ChairMolecular mechanisms of cell signaling and applications to cancer biology
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Hogle, James
Edward S. Harkness ProfessorVirus structure, mechanism of entry into cells, and replication
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Hu, Guo-Fu
Assistant ProfessorAngiogenin and its role in disease: angiogenesis, cancer, neurodegenerative diseases
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Johnson, Robert Paul
Associate ProfessorHIV mechanism of action and new AIDS therapies
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Kassis, Amin
ProfessorRadiolabeled small molecule prodrugs for non-invasive cancer imaging and therapy
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Kaur, Amitinder
Assistant ProfessorAIDS pathogenesis and CMV opportunistic infection: SIV; vaccine; AIDS resistance
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Lahav, Galit
Assistant ProfessorThe p53 tumor suppressor as a model for studying temporal dynamics of signaling networks
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Mansfield, Keith
Associate ProfessorInfectious diseases and aging: simian AIDS; opportunistic infection; diet
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Perrimon, Norbert
ProfessorModeling developmental processes and signaling pathways in Drosophila
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Qin, Xuebin
Assistant ProfessorImmune modulation to treat cancer and viral infections
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Reck-Peterson, Samara
Assistant ProfessorIntracellular cargo movement: the role of molecular motors
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Roth, Frederick
Associate ProfessorGenomic and computational analysis of genetic interactions: protein interactions; gene function; humanized yeast and drug screening; DNA sequencing
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Rowlett, James
Associate ProfessorAnxiety, addiction, cognition, and sleep: pharmacotherapy, GABA receptor
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Sharpe, Arlene
ProfessorT-cell regulation and disease: chronic viral infection; autoimmunity, tumor immunotherapy, peripheral tolerance
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Shi, Yang
ProfessorHistone demethylation and gene regulation: gene expression; epigenetics; disease
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Silver, Pamela
ProfessorSystems and synthetic biology: gene expression; synthetic proteins; biofuel
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Sinclair, David
ProfessorSirtuins in aging and disease: calorie restriction; mitochondria; cancer; diabetes
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Sorger, Peter
ProfessorSystems biology applied to disease mechanisms and drug therapy
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Van Oijen, Antoine
Assistant ProfessorSingle molecule imaging for uncovering molecular mechanisms of action: biologic and therapeutic analysis
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Van Vactor, Jr, David
ProfessorCell biology of neuronal connectivity: axon guidance; synapse; signaling mechanisms
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von Andrian, Ulrich
ProfessorAdaptive immunity and leukocyte trafficking: lymphocyte activation; lymphatic system; intravital microscopy
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Wagner, Gerhard
Elkan Blout ProfessorNMR spectroscopy for analyzing protein structure/function relationships; small molecule screening
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Weitz, Charles
ProfessorBiological mechanisms of circadian clocks and their roles in metabolic processes
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Westmoreland, Susan
Assistant ProfessorNeuropathology of HIV and SIV infections and AIDS
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Winston, Fred
ProfessorMechanisms of eukaryotic gene expression in yeast: transcriptional regulation; chromatin structure
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Wu, Chao-ting
ProfessorChromosomal homology, pairing, and segregation: mechanisms and implications for gene therapy, development, and human disease
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Yang, Priscilla
Assitant ProfessorHost response to viral infection and drug discovery: dengue virus, hepatitis B and C viruses
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Yankner, Bruce
ProfessorMolecular mechanisms of aging and aging-related neurodegenerative diseases
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Yao, Wei-Dong
Assistant ProfessorDopamine signaling; synaptic plasticity; neurobiology of neuropsychiatric and neurodegenerative disorders
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Yellen, Gary
ProfessorIon channel structure and function; epilepsy; fluorescent biosensors
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