OTD protects academic principles and independence while advancing discoveries toward commercial development.

Selected Harvard Start-ups (2005-2009)

Impact on Economic Development

Financing: $913MM (est. raised)
Number of Jobs Created: 560 (est.)

Company Year Founded Harvard Inventor(s) Harvard Technology Company Location Lead Investors
Spaced Education, Inc.
www.spaceded.com
2009 B. Price Kerfoot New on-line education technology designed for social, mobile world to improve learning retention Waltham, MA Private investment
ConstructSecure, Inc.
www.constructsecure.com
2009 Garrett Burke, Ming Chow Cost effective and efficient method to pre-qualify contractors and sub-contractors for safety performance Marlborough, MA Private investment
Diagnostics-for-All
www.dfadx.org
2009 George Whitesides Paper-based microfluidic chip the size of a fingernail Cambridge, MA
CryoXtract
www.alliedminds.com
2008 Dale Larsen Robotic system that increases the efficiency of frozen sample-handling operations Quincy, MA Allied Minds
Trophos Energy, Inc.
www.trophosenergy.com
2008 Peter Girguis Novel microbial fuel cell technology Somerville, MA Forge Partners
Crimson Hexagon, Inc.
www.crimsonhexagon.com
2008 Gary King Sentiment analysis of unstructured text Cambridge, MA Golden Seeds
Vista Therapeutics, Inc.
www.vistatherapeutics.org
2008 Charles Leiber Nanowire based biosensor for detection of biomarkers associated with organ or tissue damage Cambridge, MA New Mexico Angels
Genocea Biosciences
www.genocea.com
2008 Darren Higgins High-throughput genomic screening for antigen discovery Cambridge, MA Morningside Group
Auguron Biosciences, Inc.
2008 Joshua LaBaer NAPPA array technology
Ruika Therapeutics
2008 Joseph Schildkraut More rapid clinical antidepressant effects with norepinephrine reuptake inhibitor or other antidepressant drugs Baltimore, MD
Eutropics Pharmaceuticals, Inc.
http://eutropics.com/
2008 Junying Yuan Development of the small molecule inhibitors of the Bcl-XL/Bak interaction Dorchester, MA
InvitroStain, Inc.
2008 Robert Westervelt Methods and apparatus for near field irradiation Wilmington, DE
Hearing Armor, LLC
2008 Rick A. Rogers Protection of hearing from sudden increases in sound energy Needham, MA Angel Investors
SiEnergy Systems
www.alliedminds.com
2008 Shriram Ramanathan Micro-scale solid oxide fuel cells Quincy, MA Allied Minds
Noank Media, Inc.
www.noankmedia.com
2007 William Fisher III Methods, media and systems for tracking content usage over a network Cambridge, MA
Aileron Therapeutics
www.aileronrx.com
2007 Gregory Verdine Harvard licensed its core platform technology for turning peptides into drugs Cambridge, MA Apple Tree Partners, Novartis Bioventure Fund
Tetraphase Pharmaceuticals
http://tphase.com
2007 Andrew Myers A technology for the total synthesis of tetracyclines by enabling their synthesis from simple building blocks Watertown, MA Mediphase Venture Partners, Fidelity Biosciences, Skyline Ventures, Flagship Ventures
Matrivax Research & Development Corp.
2007 John Mekalanos Development of a novel vaccine production method and process Boston, MA Morningside Group
Incytu, Inc.
www.incytu.com
2007 David J. Mooney The cellarium(TM) technology enables reprogramming and targeting of cells to treat diseases in-vivo Lincoln, RI Private Investment
Claros Diagnostics
www.clarosdx.com
2006 George Whitesides A portable microfluidic diagnostic device Woburn, MA Oxford Bioscience Partners
Raindance Technologies
raindancetechnologies.com
2006 David Weitz Novel microfluidic techniques for droplet manupalutation for high throughput screening Guilford, CT Private investment
SiOnyx
www.sionyx.com
2006 Eric Mazur A new type of material that absorbs light very efficiently and can be used in a variety of applications Cambridge, MA Harris & Harris Group (NY)
Syndexa Pharmaceuticals
www.syndexa.com
2006 Gokhan Hotamisligil Portfolio of drug targets, assays and lead compounds for the treatment of metabolic diseases Cambridge, MA Private investment
IDEA International, Inc.
www.ideadental.com
2006 Bruce Donoff Innovative education and training method using a three-dimensional, haptic-enabled dental simulator Las Vegas, NV
Veroscience LLC
www.cycloset.com
2006 Allan Oseroff Light induced killing of carcinoma cells Tiverton, RI
Codon Devices, Inc.
2005 George Church The technology enables the accurate and inexpensive assembly of long DNA molecules useful in cell engineering and whole genome sequencing applications Cambridge, MA Flagship Ventures, Kleiner Perkins Caufield and Byers, Alloy Ventures, Khosla Ventures
Sirtris Pharmaceuticals, Inc.
www.sirtrispharma.com
2005 David Sinclair Drug discovery platform and lead compounds around sirtuins for the treatments of age related disorders Cambridge, MA Polaris Venture Partners, Skyline Ventures
NanoTerra
www.nanoterra.com
2005 George Whitesides Key technologies in soft litography, self-assembly, surface chemistry, and fluidics and their application to new manufacturing techniques Cambridge, MA Private investment
Nanotrope, Inc.
www.nanotrope.com
2005 Howard Stone Nanoscale droplet technology providing high-precision, digital control of biochemical processes San Diego, CA