Erika Bechtold

Director of Technology Commercialization, Wyss Institute

Displaying: 1 - 5 of 5 Results

Mechanically-induced regeneration

Skeletal muscle and satellite cells are sensitive to biophysical and microenvironmental cues, and there is evidence that physical manipulation of damaged muscle may promote recovery. David Mooney’s lab has used biphasic ferrogel scaffolds to create…

Investigators

  • David J. Mooney

Polymeric material for dentin restoration

David Mooney’s lab has demonstrated the use of triacrylates TMPTA and PETA as tools for the repair of dental tissues. They found that dental pulp stem cells (DPSCs) adhered to these triacrylate polymers, which had been cured by visible light, and…

Investigators

  • David J. Mooney

Tough hydrogel-based tissue adhesives

Existing adhesives are currently insufficient to bind to biological tissues, because they cannot bind strongly to wet or dynamic surfaces. David Mooney’s lab has used a bio-inspired design to create a new tough adhesive (TA) that consists of two…

Investigators

  • David J. Mooney

Materials presenting Notch signaling molecules to control cell behavior

This technology has direct application to stem cell therapy, regenerative medicine, and tissue engineering in vivo (in the patient) and in vitro (in tissue culture dish). -In vitro stem cell manipulation- Using this method of introducing Notch…

Investigators

  • David J. Mooney
  • Lan Cao
  • Kamal Bouhadir

Controlled delivery of TLR agonists in structural polymeric devices

Scientist at the Mooney lab demonstrated that three different types of pathogens could be incorporated to act as adjuvant in cancer vaccines. They have successfully incorporated three Toll-like receptor agonists (TLR) within a structural polymeric…

Investigators

  • David J. Mooney
  • Omar Abdel-Rahman Ali
  • Glenn Dranoff

Page 1 of 1