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COVID-19
Harvard faculty across the university are engaged in urgent research efforts to stem the tide of the COVID-19 pandemic and ensure preparedness for future outbreaks. We invite you to browse the projects below and consider areas within your expertise where additional academic-industry collaboration could accelerate these efforts to make a difference and save lives.
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Displaying: 1 - 10 of 10 Results
Rapid point-of-care COVID-19 detection assay by RT-LAMP
The current SARS-CoV-2 pandemic has created an urgent need for rapid point-of-care diagnostic tools. Many of these tests are being developed and are achieving FDA approval. In the face of a sweeping pandemic, assays should require no specialized…
Investigators
- Constance Cepko
Extracellular vesicles for COVID-19 vaccine development
The laboratory of Quan Lu at the Harvard T.H. Chan School of Public Health has developed an innovative vaccine platform that features a novel antigen display technology that has been shown to elicit broadly neutralizing antibody responses from…
Investigators
- Quan Lu
Red blood cell-hitchhiking to boost delivery of antivirals and immunotherapies to the lungs
Researchers in Samir Mitragotri’s lab have developed a way to traffic therapeutics directly to the lungs following routine intravenous injection and hope to apply the technology to treatment of acute respiratory distress syndrome (ARDS) and…
Investigators
- Samir Mitragotri
Oral delivery of vaccines
Researchers in Samir Mitragotri’s lab have developed a platform technology that can deliver vaccines through oral administration. The technology features ionic liquids, salts that exist in the liquid phase at room temperature, that preserve protein…
Investigators
- Samir Mitragotri
Ionic liquid aerosols for respiratory complications related to COVID-19
Researchers in the lab of Samir Mitragotri have developed ionic liquid aerosols that have the potential to combat pulmonary bacterial infections. The technology may help to treat the respiratory conditions resulting from COVID-19 infection and…
Investigators
- Samir Mitragotri
Repurposing of therapeutics to block SARS-CoV-2 protease activity and pathogenesis
Researchers in Christina Woo’s lab are studying the essential mechanisms by which SARS-CoV-2 (novel coronavirus) co-opts normal cellular processes for viral replication. One mechanism that the team has identified indicates that the virus encodes…
Investigators
- Christina Woo
Utilizing the herpes simplex virus-based vaccine vectors to develop a COVID-19 vaccine
Researchers in the lab of David Knipe have constructed the HSV-1 based vaccine vector HSV-1 d106S. The vector can express viral, bacterial, or cancer gene products and has been used to induce protective immunity in humanized mice against HIV and…
Investigators
- David Knipe
Machine learning to accelerate diagnostics and therapeutics for COVID-19
The COVID-19 pandemic demands a rapid response of science, diagnostics, and therapeutics. Debora Marks’ lab at Harvard Medical School aims to accelerate those efforts using predictive models of the SARS-CoV2-19 sequences and 3D structures. The lab’s…
Investigators
- Debora Marks
Novel adjuvants to enhance adaptive immune response of vaccines
Researchers in the lab of Ulrich von Andrian have discovered a novel adjuvanting behavior of a clinically approved and well-tolerated class of medicines known as bisphosphonates. The team is hoping to collaborate with manufacturers of COVID-19…
Investigators
- Ulrich von Andrian
Self-adjuvanting mRNA platform technology
Researchers in the lab of Prof. George Church at Harvard Medical School have developed a vaccine platform technology that can be applied to fields such as infectious diseases and oncology therapeutics. The team is looking to further demonstrate…
Investigators
- George Church