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Cardiovascular/Metabolic Disease
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Displaying: 11 - 13 of 13 Results
Targeted inhibition of the SREBP-mediator interaction as a novel therapeutic
While most therapeutic approaches aimed at altering gene expression programs target upstream signaling pathways or nuclear translocation checkpoints, Scientists at the Wagner lab have provided mechanistic insights supporting an alternative approach,…
DBD
- Grant Zimmermann
Investigators
- Gerhard Wagner
- Anders Naar
- Haribabu Arthanari
Bioinspired soft-actuated materials, cardiac simulator, and direct cardiac compression device
This invention is a medical device that utilizes soft-actuated materials for a range of biomedical applications, including simulation, rehabilitation, mechanical assistance, or complete replacement of muscular organs. High-potential, specific…
DBD
- Sam Liss
Investigators
- Conor Walsh
- Ellen Roche
- Steven Obiajulu
- Frank Pigula
- David Mooney
Biomimetic heart valve replacement
Researchers from the Disease Biology Group at Harvard have developed tissue-engineered replacement heart valves with a composition, multiscale architecture, and mechanical properties that mimic native valves. The researchers utilize a novel “jet…
Investigators
- Kevin Parker