Keyword Search
Search Results
Displaying: 1-10 of 14 Results
3D-brain organoids: Enabling discovery through patient-derived brain organoids
The Arlotta team is developing a 3D brain organoid platform, which makes it possible to study aspects of human brain development and…
Investigators:
Paola Arlotta
Giorgia Quadrato
A drug discovery platform using novel labeled uridine analogs contribute to molecular biology research
This invention consists of novel 5-amino deoxyribouridine analogs. The analogs are labeled with a radioactive or fluorescent moiety and…
Investigators:
Gregory Verdine
Michael Storek
A transgenic reporter system can be used for recombination-mediated modulation of gene activity in the developing mouse embryo
A transgenic reporter system consisting of a tamoxifen-inducible form of Cre recombinase (Cre-ERTM) that can be used for…
Investigators:
Andrew McMahon
Paul Danielian
David Rowitch
Digital DNA Storage System
A startup emerging from George Church's lab intends to leverage new enzymatic approaches to develop a cost-effective digital DNA storage…
Investigators:
George Church
Directed evolution of proteins and nucleic acids using nonhomologous random recombination
The nonhomologous random recombination (NRR) method allows portions of nucleic acids to be recombined at sites where there is little or no…
Investigators:
David Liu
Joshua Bittker
Enhanced fidelity of sub-nanogram amplification
The importance of nucleic acid amplification from trace amounts of biological sample has increased with the expansion of genomic sequencing…
Investigators:
George Church
Kun Zhang
Immunology and Computational Biology Partnership
Professors Diane Mathis and Christophe Benoist at Harvard Medical School, together with other world-renowned immunologists and computational…
Investigators:
Diane Mathis
Christophe Benoist
Mass spectrometry-based in vitro kinome activity assay
This technology is a new generation, high-throughput assay to quantitatively assess the activity of the kinome in a variety of samples.…
Investigators:
Steven Gygi
Judit Villen
Kazuishi Kubota
Yong Yu
Method for large-scale production of differentiated neurons
INTRODUCTIONHuman pluripotent stem cells (hPSC’s) can be used to generate a wide variety of somatic cell types. In addition, they…
Investigators:
Lee Rubin
Oligopaints as a means for marking chromosomes with superior resolution and labeling functionality
Oligopaints could provide a means for marking chromosomes with superior resolution and labeling functionality than currently commercially…
Investigators:
Chao-ting Wu
George Church
Benjamin Williams