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A fusion intermediate state of HIV-1 gp41, targeted by broadly neutralizing antibodies, for purposes of vaccination
HIV infection generally induces a strong antibody response to the envelope glycoprotein, the sole antigen on the virion surface. Most of…
Investigators:
Stephen Harrison
Gary Frey
Bing Chen
Attenuated RNA viruses for vaccine and drug delivery
Research in the lab of Prof. Sean Whelan has revealed new compositions to attenuate non-segmented negative-sense RNA (nsNS) viruses.…
Investigators:
Sean Whelan
Jianrong Li
Investigators:
Peter Girguis
Clare Reimers
Compounds that block human cytomegalovirus by targeting the nuclear egress complex
Researchers in Dr. Donald Coen’s lab have identified molecules that inhibit human cytomegalovirus (HCMV) virion egress from the cell,…
Investigators:
Donald Coen
Engineered Microbe Drug-Delivery Platform
Emerging startup: George Church's lab has developed a symbiotic drug-delivery platform. (Image courtesy of Anik Debnath/Tenza.)…
Investigators:
George Church
Environmentally Safe, First-in-Class Mosquito Sterilant
Dr. Flaminia Catteruccia from the Harvard T.H. Chan School of Public Health has discovered a biopesticide that is capable of sterilizing…
Investigators:
Flaminia Catteruccia
Extracellular vesicles for COVID-19 vaccine development
The laboratory of Quan Lu at the Harvard T.H. Chan School of Public Health has developed an innovative vaccine platform that features a…
Investigators:
Quan Lu
Homozygous IKKepsilon knockout mouse as an animal model for influenza virus infection
Homozygous IKKepsilon (inhibitor of kappaB kinase epsilon) mutant mice are used as animal models for influenza virus infection. Homozygous…
Investigators:
Thomas Maniatis
Benjamin tenOever
Ionic liquid aerosols for respiratory complications related to COVID-19
Researchers in the lab of Samir Mitragotri have developed ionic liquid aerosols that have the potential to combat pulmonary bacterial…
Investigators:
Samir Mitragotri
Mutated IdsD proteins for treatment of Proteus mirabilis infections
Proteus mirabilis is part of the normal flora of the human gastrointestinal tract. It can also be found free living in water and soil.…
Investigators:
Karine Gibbs