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Displaying: 1-10 of 31 Results

• A fusion intermediate state of HIV-1 gp41, targeted by broadly neutralizing antibodies, for purposes of vaccination

  HIV infection generally induces a strong antibody response to the envelope glycoprotein, the sole antigen on the virion surface. Most of…

  Investigators:
  Stephen Harrison
  Gary Frey
  Bing Chen
  
  Case #: 3133

• A genetically modified herpes simplex virus that has utility as a drug screening tool

  Harvard Medical School researchers have developed a genetically modified herpes simplex virus that has utility as a drug screening tool. To…

  Investigators:
  David Knipe
  Elizabeth McNamee
  Travis Taylor
  
  Case #: 1546

• Antimicrobial agents targeting Gram-negative bacteria

  Infections by multiple antibiotics-resistant bacteria have become a significant medical problem. However, the development of new antibiotics…

  Investigators:
  Jon Beckwith
  Dana Boyd
  
  Case #: 4891

• Antiviral targets in the ribosome

  Despite the availability of vaccines, rabies, measles, mumps, and other diseases caused by viruses of the order Mononegavirales remain…

  Investigators:
  Sean Whelan
  
  Case #: 3974

• Attenuated RNA viruses for vaccine and drug delivery

  Research in the lab of Prof. Sean Whelan has revealed new compositions to attenuate non-segmented negative-sense RNA (nsNS) viruses.…

  Investigators:
  Sean Whelan
  Jianrong Li
  
  Case #: 2568

• Bacteria based PrP and Amyloid technology generates novel aggregation assays

  Scientists at the Hochschild lab have directly exploited the ability of E. coli cells to assemble Amyloid fibers at the cell surface to…

  Investigators:
  Ann Hochschild
  Viknesh Sivanathan
  
  Case #: 4406

• Biological method to remove hydrogen sulfide from gas streams.

  Investigators:
  Peter Girguis
  Clare Reimers
  
  Case #: 3954

• Efficient collection of infectious agents from exhaled breath

  Understanding aerosol emissions is essential to developing and deploying public health interventions to combat infectious diseases.…

  Investigators:
  Petros Koutrakis
  Stephen Ferguson
  Jack Wolfson
  Donald Milton
  James McDevitt
  
  Case #: 3349

• Engineered Microbe Drug-Delivery Platform

  Emerging startup: George Church's lab has developed a symbiotic drug-delivery platform. (Image courtesy of Anik Debnath/Tenza.)…

  Investigators:
  George Church
  
  Case #:

• Environmentally Safe, First-in-Class Mosquito Sterilant

  Dr. Flaminia Catteruccia from the Harvard T.H. Chan School of Public Health has discovered a biopesticide that is capable of sterilizing…

  Investigators:
  Flaminia Catteruccia
  
  Case #: 5746