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Evolution of Sequence-Defined Highly Functionalized Nucleic Acid Polymers
DESCRIPTION Template-directed synthesis of modified DNA sequences can provide a rich source of material for generating new therapies…
Investigators:
David Liu
In vivo gene editing in dystrophic muscle
Duchenne Muscular Dystrophy (DMD) is a debilitating disease caused by the absence of dystrophin, a protein expressed in muscle fibers. …
Investigators:
Amy Wagers
Mechanically-induced regeneration
Skeletal muscle and satellite cells are sensitive to biophysical and microenvironmental cues, and there is evidence that physical…
Investigators:
David Mooney
Modulating gene activity on chondrocytes
Transgenic mice were generated in which the regulatory sequences for the Col2a1 gene were used to drive expression of Cre recombinase in…
Investigators:
Andrew McMahon
Fanxin Long
Regenerative Cell Therapy for Skeletal Muscle Disorders
A startup emerging from Lee Rubin's lab aims to provide a long-term cell therapy regenerative solution for conditions that result in…
Investigators:
Lee Rubin