Harvard's Office of Technology Development and LabCentral invite you to the latest event in the Guppy Tank series, where two teams of Harvard life-science innovators will pitch their concepts to a panel of entrepreneurs and investors for constructive, in-depth feedback.
Please join us on May 16 from 4 to 6 p.m. to learn from experts on startup formation and participate in giving audience feedback. Networking reception to follow.
This month's innovation teams:
Neurox — Functional enhancers of neuronal connectivity
Rock Liao and Mike Greenberg, Harvard Medical School
Small molecules that act as synaptic growth enhancers and also correct brain-specific gene misregulation have been identified via a highly optimized phenotypic screening platform. The compounds, validated so far in models of Alzheimer’s disease and traumatic brain injury, may be used to treat a broader range of neurodevelopmental and neurodegenerative disease indications. The team will describe the screening strategy and results, and will be seeking advice regarding potential preclinical and clinical development strategies.
Carica Health — Take charge of neuroinflammation!
David Roberson, Bruce Levy, Clifford Woolf and Bruce Bean (Harvard Medical School, Boston Children’s Hospital, Brigham & Women’s Hospital)
CariCations are charged versions of clinically used sodium channel blockers that are designed to be used topically to selectively silence cough, pain, itch and — thanks to their prolonged effect — also a multitude of inflammatory conditions. The team will share in vivo efficacy data of its proprietary compounds and look for input regarding target indications and clinical and commercial strategies.