Stat4 Knock Out mice
Mice homozygous for the Stat4tm1Gru mutation are viable and fertile. IL12 induced interferon-gamma secretion and stimulation of lymphocytes are defective. Development of Th1 cells in response to either IL12 or Listeria monocytogenes is also defective with propensity towards Th2 cells. The Jackson Laboratory 2024, used with permission.
Jax Stock Number:
2826
Additional Information
Jax Stock Number: 2826