Yelena Bisharyan

Director of Business Development

Displaying: 21 - 30 of 31 Results

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Vmn1r50/Tau-LacZ Transgenic Mice

Vmn1r50 (vomeronasal 1 receptor 50; also called VN2) is a member of the vomeronasal organ V1R gene family, whose activation is believed to be involved with pheromone detection. These mice co-express tau-lacZ with pheromone receptor Vmn1r50, enabling…

Research Tool

Tg(Thy1-Brainbow3.1) Transgenic Mice

The Thy1-Brainbow 3.1 transgene was designed by Drs. Dawen Cai and Joshua R.Sanes (Harvard University) with the mouse Thy1 (thymus cell antigen 1, theta) regulatory elements surrounding four fluorescent protein (Yellow fluorescent protein…

Investigators

  • Joshua R. Sanes
  • Joshua R. Sanes

Research Tool

Brsk1Knock Out Mice

The protein encoded by Brsk1 is a serine/threonine-protein kinase that is involved in neuronal polarization, axon branching, and presynaptic differentiation in diverse neuronal populations. These mice carry a targeted mutation of the Brsk1 gene in…

Investigators

  • Joshua R. Sanes
  • Joshua R. Sanes

Research Tool

Brsk2Floxed Transgenic Mice

The protein encoded by Brsk2 is a serine/threonine-protein kinase that is involved in neuronal polarization, axon specification, axon branching, and presynaptic differentiation in diverse neuronal populations. These mice possess loxP sites on either…

Investigators

  • Joshua R. Sanes
  • Joshua R. Sanes

Research Tool

Hist2h2be Targeted Mutation Mice

Hist2h2be (histone cluster 2, H2be) is expressed exclusively in olfactory chemosensory neurons. Expression is reduced by sensory activity, and it alters gene expression and promotes neuronal cell death in mature olfactory sensory neurons,…

Research Tool

Hist2h2be Flag-Tagged Transgenic Mice

Hist2h2be (histone cluster 2, H2be) is expressed exclusively in olfactory chemosensory neurons. Expression is reduced by sensory activity, and it alters gene expression and promotes neuronal cell death in mature olfactory sensory neurons,…

Research Tool

Tbet-cre Transgenic Mice

These transgenic mice express Cre recombinase from the mouse Tbx21 (T-box 21; also called Tbet) promoter in mitral cells of the main and accessory olfactory bulbs. Surveys of the rest of the brain show that Cre-induced recombination is specific to…

Research Tool

Mif Knock Out Mice

These mice have a neo cassette disrupting exons 2-3 of the macrophage migration inhibitory factor (glycosylation-inhibiting factor) (MIf) gene, abolishing gene expression. MIF is a lymphokine involved in cell-mediated immunity, immunoregulation, and…

Investigators

  • John R. David

Research Tool

Vmn1r232/EGF Transgenic Mice

Vmn1r232 (vomeronasal 1 receptor 232; also called V1Re4) is a member of the vomeronasal organ V1R gene family, whose activation is believed to be involved with pheromone detection. Inputs from neurons expressing closely related V1Rs intermingle…

Invention

Regeneration of Skin Tissue

The amazing regenerative capability of fetal skin has been known for decades. While postnatal skin heals through fibrosis (scar formation) and only the epidermis can be restored, fetal skin has enormous regenerative capability and heals without scar…

Investigators

  • Ya-Chieh Hsu

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