Skip to main content

Search Results

Displaying: 181 - 190 of 266 Results

Improved performance of copper interconnects

Copper (Cu) is now the preferred material for interconnections in ICs because it conducts better and lasts longer than aluminum. However, there are well-known problems with copper interconnects. Copper tends to migrate out of the wiring, degrading…

DBD

  • Christopher Petty

Investigators

  • Roy Gordon
  • Yeung Au
  • Youbo Lin
  • Harish Bhandari

Silicon-based photodiodes for enhanced infrared detection, quick response and low cost

The technology offered here is for the creation of an “impurity enhanced” silicon material with unique optelectric properties. The material is created by employing an ion-implantation technique using a nanosecond laser to melt the basis of single…

DBD

  • Christopher Petty

Investigators

  • Michael Aziz
  • Daniel Recht
  • Aurore Said
  • Jeffery Warrender

Trioxacarcins and analogs: DNA-modifying compounds with potent anti-proliferative effects

The trioxacarcins are a new class of DNA-modifying natural products with potent antiproliferative effects (with subnanmolar IC70 values against lung, mammary, and CNS cancer cell lines). Trioxacarcin A, B, and C were first discovered and isolated…

DBD

  • Yelena Bisharyan

Investigators

  • Andrew Myers
  • Jakub Svenda
  • Nicholas Hill
  • Robert Yu
  • Daniel Smaltz
  • Thomas Magauer

High-flux, low-power diamond nanowire single-photon source arrays: an enabling material for optical and quantum computing and cryptography

The novel approach taken by the Harvard researchers was to apply top-down nanofabrication techniques to define large arrays of vertically oriented nanowire antennas in a single-crystal diamond substrate. Briefly, structures were made from a…

DBD

  • Sam Liss

Investigators

  • Marko Loncar
  • Thomas Babinec
  • Birgit Yao
  • Mughees Khan
  • Yinan Zhang
  • Philip Hemmer

Small molecule inhibitors of Ebola virus entry

Background: Human cells that are susceptible to infection by pathogenic viruses express surface membrane proteins that mediate attachment and membrane fusion activity of virus glycoproteins. There are strong structural and functional similarities…

DBD

  • Irit Ben-Chelouche

Investigators

  • Dennis Kasper
  • Kyungae Lee
  • Tao Ren
  • James Cunningham
  • Kartik Chandran

Analyzing trace gases at part-per-billion levels by rapid gas-phase cooling

This invention realizes a new idea of using buffer gas to rapidly cool small gas molecules to very low temperatures.

DBD

  • Christopher Petty

Investigators

  • John Doyle
  • David Patterson

Materials presenting Notch signaling molecules to control cell behavior

This technology has direct application to stem cell therapy, regenerative medicine, and tissue engineering in vivo (in the patient) and in vitro (in tissue culture dish). -In vitro stem cell manipulation- Using this method of introducing Notch…

Investigators

  • David Mooney
  • Lan Cao
  • Kamal Bouhadir

High-sensitivity, high-throughput biosensor capable of detecting biomarkers without external fluorescent labels

This invention describes a combination of technologies that produce a miniature optical biosensor array which is capable of detecting biomarkers without requiring external fluorescent labels. This label-free approach uses a sample placed in a…

DBD

  • Sam Liss

Investigators

  • Frank Vollmer
  • Qimin Quan
  • Marko Loncar

Phaeobacticides - Potent and selective new class of algae growth inhibitors

Algae are a diverse group of uni- and multicellular plants that grow in water. Undesired and uncontrolled algal blooms are a recurring problem in bodies of water such as swimming pools, aquaculture ponds, aquariums, industrial drainage systems and…

DBD

  • Grant Zimmermann

Investigators

  • Jon Clardy
  • Roberto Kolter
  • Mohammad Seyedsayamdost
  • Rebecca Case

Small-molecule macrocycles: Potent and selective Src kinase inhibitors

Macrocyclic compounds have unique properties that allow them to cover regions of chemical space not addressed by other small-molecule structural classes. By performing an in vitro selection screen of a broad untargeted DNA-encoded library of 13,824…

DBD

  • Irit Ben-Chelouche

Investigators

  • David Liu
  • Ralph Kleiner

Page 19 of 27