September 01, 2014

August 2014 patents: peptides, cyclic metal amides, and more

Shigemi Nagai, Masazumi Nagai, Mindy Sungmin Gil
Peptides and peptide compositions having osteoinductive activity: 8,815,807

Compositions and kits are provided having a peptide having an amino acid sequence that binds to eukaryotic cells and effects differentiation and support growth of the cells. Peptide-scaffold compositions containing at least one peptide or combinations of peptides are therapeutic agents for stimulating and promoting osteogenic activity and osteoinduction activity for cells. The scaffold is for example apatite, natural cancellous bone, demineralized natural cancellous bone, collagen, calcium phosphate, or hydroxyapatite.


Roy G. Gordon, Adam S. Hock, Jaeyeong Heo, Prasert Sinsermsuksakul
Cyclic metal amides and vapor deposition using them: 8,796,483

Novel cyclic amides containing tin or lead are disclosed. These cyclic amides can be used for atomic layer deposition or chemical vapor deposition of tin or lead as well as their oxides, sulfides, selenides, nitrides, phosphides, carbides, silicides or borides or other compounds. Tin(IV) oxide, SnO.sub.2, films were deposited by reaction of a cyclic tin amide vapor and H.sub.2O.sub.2 or NO.sub.2 as oxygen sources. The films have high purity, smoothness, transparency, electrical conductivity, density, and uniform thickness even inside very narrow holes or trenches. Deposition temperatures are low enough for thermally sensitive substrates such as plastics. Suitable applications of these films include displays, light-emitting diodes, solar cells and gas sensors. Doping SnO.sub.2 with aluminum was used to reduce its conductivity, making material suitable as the active semiconductor layer in electron multipliers or transparent transistors. Deposition using the same tin precursor and H.sub.2S deposited tin monosulfide, SnS, a material suitable for solar cells.


Wesley Philip Wong, Kenneth Anders Halvorsen
Spinning force apparatus: 8,795,143

Loren D. Walensky, Stanley J. Korsmeyer, Gregory L. Verdine
Stabilized alpha helical peptides and uses thereof: 8,796,418

Qimin Quan, Marko Loncar
High quality factor photonic crystal nanobeam cavity and method of designing and making same: 8,798,414

Amber T. Krummel, David A. Weitz
Surfaces, including microfluidic channels, with controlled wetting properties: 8,802,027

Amit Meller, Jerome Mathe, John S. Eid
Ultra high-throughput opti-nanopore DNA readout platform: 8,802,838

Jie Zheng, Xiaowei Zhuang
Granular nanoparticles having bright fluorescence and giant raman enhancements: 8,815,158

Shriram Ramanathan, Alexander C. Johnson
Micro-scale energy conversion devices and methods: 8,815,466


Find more details about these and all Harvard patents at the USPTO website.

Press Contact

Caroline Perry, (617) 495-4157
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Press Contact

Caroline Perry
(617) 495-4157
Email