Vivian Berlin

Executive Director, HMS

Displaying: 71 - 75 of 75 Results

Research Tool

Ngn3/CreER Trangenic Mice

These transgenic mice have a tamoxifen inducible Cre-mediated recombination system driven by the mouse neurogenin 3, Neurog3, promoter. The transgene insert contains a fusion product involving Cre recombinase and a mutant form of the mouse estrogen…

Investigators

  • Douglas Melton

Research Tool

B6(D2)-Tg(CAG-Brainbow1.0)3 Transgenic Mice

These transgenic mice carry the Brainbow 1.0 cassette, incorporating dTomato, mCerulean, and EYFP, driven by the broadly-expressed CAG (CMV-chicken beta actin) promoter. These fluorescent markers are useful in tracing cell lineage. This strain, line…

Investigators

  • Kevin Carl Eggan

Research Tool

Six2-GCE Targeted Mutation Mice

While heterozygous mice are viable and fertile with no reported abnormalities, homozygous mice die shortly after birth. The Six2GCE "knock-in" allele both abolishes Six2 gene function and expresses an eGFPCreERT2 fusion protein (EGFP and creERT2…

Investigators

  • Andrew P. McMahon

Research Tool

Ihh Transgenic Mice

Mice heterozygous for this targeted mutation are viable and fertile. Homozygotes die from respiratory failure shortly after birth. Expression of the "knocked-in" lacZ gene is detected in a pattern similar to the endogenous transcript (in lung,…

Investigators

  • Andrew P. McMahon

Research Tool

Wnt5 Knock Out Mice

Homozygous null mice have a perinatal lethal phenotype and do not survive long after birth due to respiratory failure. Mice that are heterozygous for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or…

Investigators

  • Andrew P. McMahon

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