Lfng-nuc-Tag-RFP-T-IRES-CE Transgenic Mice

These Lfng-nuc-Tag-RFP-T-IRES-CE mutant mice have a tamoxifen inducible Cre-mediated recombination system and express the Tag-RFPT variant of Red Fluorescent Protein under the direction of the mouse Lfng, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, promoter. RFP fluorescence is not detected in wholemount embryos. Transgene expression is detected using immunohistochemistry in developing renal vesicles in the kidney of hemizygotes at 15.5 embryonic days of age. Tamoxifen inducible Cre recombinase activity is detected in a subset of Tag RFP-T positive cells in the kidney. Mice that are hemizygous for the knock in allele are viable, fertile, normal in size and do not display physical or behavioral abnormalities. This strain was transferred from the collection of the GenitoUrinary Development Molecular Anatomy Project (GUDMAP). The Jackson Laboratory 2024, used with permission.

Jax Stock Number: 17496