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Displaying: 101 - 110 of 139 Results
Wnt1-lacZ Transgenic Mice
These transgenic mice show no phenotypic defects. LacZ is expressed in the dorsal CNS. This strain is useful as a marker for CNS development, specifically for the migrating cranial and trunk neural crest. The Jackson Laboratory 2024, used with…
Investigators
- Laurie Glimcher
Wnt3a Knock Out Mice
Mice that are heterozygous for the targeted mutation are viable, fertile, normal in size and, with the exception of a kinked tail, do not display any gross physical or behavioral abnormalities. Homozygous null mice have an embryonic lethal…
DBD
- Vivian Berlin
Investigators
- Andrew McMahon
Wnt4 Knock Out Mice
Mice that are heterozygous for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Homozygous null mice have a perinatal lethal phenotype and die within 24 hours of birth.…
DBD
- Vivian Berlin
Investigators
- Andrew McMahon
Wnt5 Knock Out Mice
Homozygous null mice have a perinatal lethal phenotype and do not survive long after birth due to respiratory failure. Mice that are heterozygous for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or…
DBD
- Vivian Berlin
Investigators
- Andrew McMahon
Wnt7a Knock Out Mice
Mice that are homozygous for the targeted mutation are viable, but sterile. A truncated mRNA transcript is detected during embryogenesis. Homozygotes exhibit ventralization of dorsal limb mesoderm tissues. The variable phenotype includes thickening…
DBD
- Vivian Berlin
Investigators
- Andrew McMahon
Wnt7b Knock Out Mice
Mice that are heterozygous for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Homozygous mice have an embryonic lethal phenotype, failing to develop past 11.5 days post…
DBD
- Vivian Berlin
Investigators
- Andrew McMahon
Wnt7bc3 LoxP Targeted Mutation Mice
Mice homozygous for the Wnt7bc3 allele are viable and fertile, with loxP sites flanking exon 3 of the targeted gene. When bred to mice that express Cre recombinase, the resulting offspring will have this region deleted in the cre-expressing…
DBD
- Vivian Berlin
Investigators
- Douglas Melton
Wnt9bc LoxP Targeted Mutation Mice
Mice homozygous for the Wnt9bc allele are viable and fertile, with loxP sites flanking exon 2 of the targeted gene. When bred to mice that express Cre recombinase, the resulting offspring will have this region deleted in the cre-expressing…
DBD
- Vivian Berlin
Investigators
- Andrew McMahon
YY1lox Targeted Mutation Mice
These mice possess loxP sites on either side of exon 1 of the targeted gene. Mice that are homozygous for this allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. When these mutant mice are…
DBD
- Irit Ben-Chelouche
Investigators
- Yang Shi
B6(D2)-Tg(CAG-Brainbow1.0)2 Transgenic Mice
These transgenic mice carry the Brainbow 1.0 cassette, incorporating dTomato, mCerulean, and EYFP, driven by the broadly-expressed CAG (CMV-chicken beta actin) promoter. These fluorescent markers are useful in tracing cell lineage. This strain, line…
DBD
- Vivian Berlin
Investigators
- Kevin Eggan