Vivian Berlin

Executive Director, HMS

Displaying: 41 - 50 of 75 Results

Research Tool

Lfng-nuc-Tag-RFP-T-IRES-CE Transgenic Mice

These Lfng-nuc-Tag-RFP-T-IRES-CE mutant mice have a tamoxifen inducible Cre-mediated recombination system and express the Tag-RFPT variant of Red Fluorescent Protein under the direction of the mouse Lfng, LFNG O-fucosylpeptide…

Investigators

  • Andrew P. McMahon

Research Tool

Wnt9bc LoxP Targeted Mutation Mice

Mice homozygous for the Wnt9bc allele are viable and fertile, with loxP sites flanking exon 2 of the targeted gene. When bred to mice that express Cre recombinase, the resulting offspring will have this region deleted in the cre-expressing…

Investigators

  • Andrew P. McMahon

Research Tool

Shh Targeted Mutation Mice

Mice that are homozygous for the Shhtm2Amc targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. This conditional mutant contains two loxP sites flanking exon 2 of the targeted…

Investigators

  • Andrew P. McMahon

Research Tool

Hoxb7-cre Transgenic Mice

Mice hemizygous for the transgenic insert are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Homozygotes are not viable. These transgenic mice express the Cre recombinase under the control of the…

Investigators

  • Andrew P. McMahon

Research Tool

Wnt3a Knock Out Mice

Mice that are heterozygous for the targeted mutation are viable, fertile, normal in size and, with the exception of a kinked tail, do not display any gross physical or behavioral abnormalities. Homozygous null mice have an embryonic lethal…

Investigators

  • Andrew P. McMahon

Research Tool

ROSA 26Sortm1(Smo/EYFP) Transgenic Mice

When these mice are used in conjunction with a Cre recombinase-expressing strain, successful Cre-mediated excision results in the constitutive expression of the Smo/EYFP fusion gene (monitored by using EYFP-specific fluorescence protocols) and…

Investigators

  • Andrew P. McMahon

Research Tool

Col1a1-tetO-H2B-mcherry Targeted Mutation Mice

These Col1a1-tetO-H2B-mcherry mutant mice contain a tet-responsive element (tetO) and a histone H2B-mCherry fusion protein, targeted to the collagen, type I, alpha 1 (Col1a1) locus. Homozygous are viable, fertile, and normal is size. Animals have a…

Investigators

  • Kevin Carl Eggan

Research Tool

Tmem100-GCE Transgemic Mice

These transgenic mice express the eGFPCreERT2 (Enhanced Green Fluorescent Protein and cre/ESR1) fusion gene under the direction of the mouse Tmem100, transmembrane protein 100, promoter. Transgene expression is detected in developing nephrons of the…

Investigators

  • Andrew P. McMahon

Research Tool

Meox1-nucTagRFP-T-IRES-CE Transgenic Mice

These Meox1-nucTagRFP-T-IRES-CE mutant mice have a tamoxifen inducible Cre-mediated recombination system and express the nuclear-localized Tag-RFPT variant of Red Fluorescent Protein under the direction of the mouse Meox1, mesenchyme homeobox 1,…

Investigators

  • Andrew P. McMahon

Research Tool

B6(D2)-Tg(CAG-Brainbow1.0)2 Transgenic Mice

These transgenic mice carry the Brainbow 1.0 cassette, incorporating dTomato, mCerulean, and EYFP, driven by the broadly-expressed CAG (CMV-chicken beta actin) promoter. These fluorescent markers are useful in tracing cell lineage. This strain, line…

Investigators

  • Kevin Carl Eggan

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