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AAV Capsid Generation Platform for Enhanced Delivery and Specificity
A startup emerging from the Church Lab aims to commercialize an AAV capsid-generation platform. (Image credit: Wyss Institute at Harvard…
Investigators:
George Church
Case #:ARMMs – Microvesicles for Non-immunogenic Nucleic Acid and/or Protein Drug Delivery
Dr. Quan Lu has discovered a novel population of naturally secreted, non-immunogenic microvesicles that can deliver nucleic acid and protein…
Investigators:
Quan Lu
Case #: HU 4400/HU 5521Electrophilic activity-based RNA probes reveal a self-alkylating RNA for RNA labeling
Probes that form covalent bonds with RNA molecules on the basis of their chemical reactivity would advance our ability to study the…
Investigators:
David Liu
Richard MacDonald
Case #: 5548Enhancers of Gene Therapy
Currently available gene therapy technologies rely on either plasmid DNA or viral vector transduction to enable gene transfer. However, such…
Investigators:
David Knipe
Case #: 4892Evasion of the Innate Immune Response for AAV Gene Therapy
A startup emerging from George Church's lab intends to develop uniquely enabled gene therapy products, using technologies that enable AAV…
Investigators:
George Church
Case #:Evolution of Sequence-Defined Highly Functionalized Nucleic Acid Polymers
DESCRIPTION Template-directed synthesis of modified DNA sequences can provide a rich source of material for generating new therapies…
Investigators:
David Liu
Case #: 6849Platform for AAV Delivery to Skin
Emerging startup: A platform technology from George Church's lab enables delivery of gene therapy via the skin. (Image credit: Carl…
Investigators:
George Church
Case #: