FAT3, an atypical cadherin protein, is expressed on amacrine cell (AC) processes in the developing and mature inner plexiform layer (IPL) of the retina and is associated with dendrite morphogenesis. These mutant mice possess loxP sites flanking exon 23 of the Fat3 gene. Mice that are homozygous for this allele are viable, fertile, and normal in size. When bred to mice that express tissue-specific Cre recombinase, resulting offspring will have exon 23 deleted in the cre-expressing tissues. This strain may be useful for studying dendrite development. The Jackson Laboratory 2024, used with permission.