Vivian Berlin

Executive Director, HMS

Displaying: 71 - 75 of 75 Results

Research Tool

Pdx1-CreER Transgenic Mice

Pancreatic cells are derived from Pdx1 (pancreatic and duodenal homeobox 1)-expressing progenitors throughout embryogenesis. This conditional transgenic strain expresses Cre/Esr1 from the mouse Pdx1 promoter. Cytoplasmic stores of Cre recombinase…

Investigators

  • Douglas Melton

Research Tool

B6N.Sox2-Cre Transgenic Mice

These transgenic mice express Cre recombinase under the control of the mouse SRY-box containing gene 2 promoter. The transgene integrated into an intron of Edil3 (EGF-like repeats and discoidin I-like domains 3). The insertion results in a…

Investigators

  • Andrew P. McMahon

Research Tool

Smo Knock Out Mice

Mice that are heterozygous for the targeted allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Homozygous null mice have an embryonic lethal phenotype, failing to develop past 9.5 days post…

Investigators

  • Andrew P. McMahon

Research Tool

KRT14-cre Transgenic Mice

Mice hemizygous for the K14-Cre transgene are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. These transgenic mice express Cre recombinase under the control of the human keratin 14 promoter. Cre…

Investigators

  • Andrew P. McMahon

Research Tool

Wnt7b Knock Out Mice

Mice that are heterozygous for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Homozygous mice have an embryonic lethal phenotype, failing to develop past 11.5 days post…

Investigators

  • Andrew P. McMahon

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