Vivian Berlin

Executive Director, HMS

Displaying: 71 - 75 of 75 Results

Research Tool

B6(D2)-Tg(CAG-Brainbow1.0)2 Transgenic Mice

These transgenic mice carry the Brainbow 1.0 cassette, incorporating dTomato, mCerulean, and EYFP, driven by the broadly-expressed CAG (CMV-chicken beta actin) promoter. These fluorescent markers are useful in tracing cell lineage. This strain, line…

Investigators

  • Kevin Carl Eggan

Research Tool

Shh::gfp Targeted Mutation Mice

While mice heterozygous for the Shh::gfp allele are viable, fertile, and indistinguishable from wild-type littermates, homozygotes are stillborn and show developmental defects consistent with reduced Sonic Hedgehog (Shh) signaling. The Shh::gfp…

Investigators

  • Andrew P. McMahon

Research Tool

Ihh Knock Out Mice

Mice that are heterozygous for the targeted allele are viable and fertile. Mice homozygous for this mutation have a lethal phenotype. Half of homozygous null mice have an embryonic lethal phenotype, dying between 10.5 to 12.5 days post coitum. The…

Investigators

  • Andrew P. McMahon

Research Tool

Wnt4 Knock Out Mice

Mice that are heterozygous for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Homozygous null mice have a perinatal lethal phenotype and die within 24 hours of birth.…

Investigators

  • Andrew P. McMahon

Research Tool

Rosa26-rtTA::Col1a1-tetO-H2B-mCherry Targeted Mutation Mice

The Rosa26-rtTA::Col1a1-tetO-H2B-mCherry double mutant mice were generated by breeding Rosa26-rtTA mice (from Stock No. 006965) with Col1a1-tetO-H2B-mCherry mice (from Stock No. 014592). The Rosa26-rtTA targeted mutation has an optimized form of…

Investigators

  • Kevin Carl Eggan

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