DBD Search
Vivian Berlin
Executive Director, HMS
Displaying: 71 - 75 of 75 Results
Research Tool
Ihh Transgenic Mice
Mice heterozygous for this targeted mutation are viable and fertile. Homozygotes die from respiratory failure shortly after birth. Expression of the "knocked-in" lacZ gene is detected in a pattern similar to the endogenous transcript (in lung,…
Investigators
- Andrew P. McMahon
Research Tool
Wnt5 Knock Out Mice
Homozygous null mice have a perinatal lethal phenotype and do not survive long after birth due to respiratory failure. Mice that are heterozygous for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or…
Investigators
- Andrew P. McMahon
Research Tool
ROSA 26Sortm1(Smo/EYFP) Transgenic Mice
When these mice are used in conjunction with a Cre recombinase-expressing strain, successful Cre-mediated excision results in the constitutive expression of the Smo/EYFP fusion gene (monitored by using EYFP-specific fluorescence protocols) and…
Investigators
- Andrew P. McMahon
Research Tool
Cited1-nuc-TagRFP-T Transgenic Mice
These transgenic mice express the Tag-RFPT variant of Red Fluorescent Protein under the direction of the mouse Cited1, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1, promoter. TagRFP is the optimized monomeric…
Investigators
- Andrew P. McMahon
Research Tool
Sox2Cre Transgenic Mice
These transgenic mice express Cre recombinase under the control of the mouse SRY-box containing gene 2 promoter. The transgene integrated into an intron of Edil3 (EGF-like repeats and discoidin I-like domains 3). The insertion results in a…
Investigators
- Andrew P. McMahon