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Platform for AAV Delivery to Skin

Emerging startup: A platform technology from George Church's lab enables delivery of gene therapy via the skin. (Image credit: Carl Schoellhammer, Denitsa Milanova, Humberto Trevino, Cody Cleveland, Jeff Wyckoff, Anna Mandinova, George Church,…

Investigators

  • George Church

Evolution of Sequence-Defined Highly Functionalized Nucleic Acid Polymers

DESCRIPTION Template-directed synthesis of modified DNA sequences can provide a rich source of material for generating new therapies featuring modified nucleic acid polymers. The Liu lab has previously developed pioneering methods to generate…

Investigators

  • David Liu

Enhancers of Gene Therapy

Currently available gene therapy technologies rely on either plasmid DNA or viral vector transduction to enable gene transfer. However, such methods often suffer from poor direct expression and insufficient incorporation of foreign genetic material.…

Investigators

  • David Knipe
  • Megan Orzalli

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