Browse Research Tools
Browse Research Tools
Research Tools Keyword Search
Search Results
Displaying: 1 - 10 of 139 Results
R26R-Confetti Targeted Mutation Mice
Mice homozygous for the R26R-Confetti conditional allele are viable and fertile, with a CAG promoter, loxP site, and STOP cassette preventing transcription of the downstream Brainbow 2.1 sequences. The Brainbow 2.1 region contains two loxP-flanked…
DBD
- Irit Ben-Chelouche
Investigators
- Jeffrey Lichtman
7B2 Knock Out Mice
While heterozygotes are viable and fertile, mice homozygous for this mutation (7B2-null) die in prepubertal or pubertal ages (5 weeks) with severe cardio-respiratory failure, convulsions, and hypothermia. No transcripts are detected in brain tissue…
DBD
- Irit Ben-Chelouche
ACTB:FLPe B6N Transgenic Mice
This transgenic strain expresses a variant of the Saccharomyces cerevisiae FLP1 recombinase gene under the direction of the human ACTB promoter. The FLPe recombinase variant exhibits enhanced thermostability with recombination activity being…
DBD
- Grant Zimmermann
Investigators
- Susan Dymecki
ACTB:FLPe Transgenic Mice
This transgenic strain expresses a variant of the Saccharomyces cerevisiae FLP1 recombinase gene under the direction of the human ACTB promoter. The FLPe recombinase variant exhibits enhanced thermostability with recombination activity being…
DBD
- Grant Zimmermann
Investigators
- Susan Dymecki
Akr1b7RFP Trangenic Mice
These transgenic mice express Red Fluorescent Protein (TagRFP-T variant) under the direction of the mouse Akr1b7, aldo-keto reductase family 1, member B7, promoter. Transgene expression is detected at high levels in the adrenal glands and…
DBD
- Vivian Berlin
Investigators
- Andrew McMahon
Arrb1 Knock Out Mice
Mice homozygous for this Arrb1 (arrestin, beta 1) targeted mutation produce a cardiac ejection fraction that is greater than that of wildtype mice in response to isoproterenol, a _-receptor agonist. They are viable and fertile and do not display any…
DBD
- Grant Zimmermann
ATF-2- Targeted Mutant Mice
Mice homozygous for this mutation show decreased postnatal survival. Many of the mice die within the first 2 days of life or at the time of weaning. The growth of the surviving homozygous mice is impaired. Homozygous mice are hyperactive, display a…
Investigators
- Laurie Glimcher
B6.129S1-Nlrp1129S1/DieJ Transgenic Mice
Mice that are heterozygous or homozygous for the "Nalp1b129S1" transgene are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Protein products from both the native and transgenic alleles of the gene…
DBD
- Maryanne Fenerjian
Investigators
- William Dietrich
B6.C3-Chr11 Cosmognic Mice
A chromosome substitution or consomic strain is an inbred strain with one of its chromosomes replaced by the homologous chromosome of another inbred strain. The C57BL/6J and C3H/HeJ inbred strains were selected for this consomic because they differ…
DBD
- Maryanne Fenerjian
Investigators
- William Dietrich
B6.C3-Chr2 Consomic Mice
A chromosome substitution or consomic strain is an inbred strain with one of its chromosomes replaced by the homologous chromosome of another inbred strain. The C57BL/6J and C3H/HeJ inbred strains were selected for this consomic because they differ…
DBD
- Maryanne Fenerjian
Investigators
- William Dietrich