Harvard Office of Technology Development

casp-11 Knock Out Mice

Caspase 4 (also known as caspase 11) is a critical upstream regulator in the caspase cascade with an important dual role in regulating both inflammatory response and apoptosis. Splenocytes harvested from homozygous mice both before and after…

DBD

Grant Zimmermann

Investigators

Junying Yuan

Pdx1-CreER Transgenic Mice

Pancreatic cells are derived from Pdx1 (pancreatic and duodenal homeobox 1)-expressing progenitors throughout embryogenesis. This conditional transgenic strain expresses Cre/Esr1 from the mouse Pdx1 promoter. Cytoplasmic stores of Cre recombinase…

DBD

Vivian Berlin

Investigators

Douglas Melton

Vmn1r232/EGF Transgenic Mice

Vmn1r232 (vomeronasal 1 receptor 232; also called V1Re4) is a member of the vomeronasal organ V1R gene family, whose activation is believed to be involved with pheromone detection. Inputs from neurons expressing closely related V1Rs intermingle…

DBD

Yelena Bisharyan

Vmn1r206/YFP Transgenic Mice

Vmn1r206 (vomeronasal 1 receptor 206; also called V1Rh7) is a member of the vomeronasal organ V1R gene family, whose activation is believed to be involved with pheromone detection. Inputs from neurons expressing closely related V1Rs intermingle…

DBD

Yelena Bisharyan

Vmn1r191/CFP Transgenic Mice

Vmn1r191 (vomeronasal 1 receptor 191; also called V1Rh15) is a member of the vomeronasal organ V1R gene family, whose activation is believed to be involved with pheromone detection. Inputs from neurons expressing closely related V1Rs intermingle…

DBD

Yelena Bisharyan

Vmn1r51/Tau-LacZ Transgenic Mice

Vmn1r51 (vomeronasal 1 receptor 51; also called VN12) is a member of the vomeronasal organ V1R gene family, whose activation is believed to be involved with pheromone detection. These mice co-express tau-lacZ with pheromone receptor Vmn1r51…

DBD

Yelena Bisharyan

Vmn1r50/Tau-LacZ Transgenic Mice

Vmn1r50 (vomeronasal 1 receptor 50; also called VN2) is a member of the vomeronasal organ V1R gene family, whose activation is believed to be involved with pheromone detection. These mice co-express tau-lacZ with pheromone receptor Vmn1r50, enabling…

DBD

Yelena Bisharyan

Cx40 Knock Out Mice

The Gja5 gene encodes an intercellular channel forming protein, also known as Connexin 40, which functions as a component of gap junctions. These mice carry a knock out mutation of the Gja5 gene in which a PGK-NEO cassette replaces the single coding…

DBD

Irit Ben-Chelouche

Cx37 Knock Out Mice

The Gja4 gene encodes an intercellular channel forming protein, also known as Connexin 37, that is a component of gap junctions. These mice carry a knock out mutation of the Gja4 gene in which a PGK-NEO cassette replaces almost the entire coding…

DBD

Irit Ben-Chelouche

Browse Research Tools