Browse Research Tools
Browse Research Tools
Research Tools Keyword Search
Search Results
Displaying: 11 - 20 of 139 Results
B6N.Sox2-Cre Transgenic Mice
These transgenic mice express Cre recombinase under the control of the mouse SRY-box containing gene 2 promoter. The transgene integrated into an intron of Edil3 (EGF-like repeats and discoidin I-like domains 3). The insertion results in a…
DBD
- Vivian Berlin
Investigators
- Andrew McMahon
Blmlox Targeted Mutation Mice
These mice possess loxP sites on either side of exon 8 of the targeted gene. Mice that are homozygous for this allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. When these mutant mice are…
DBD
- Irit Ben-Chelouche
Investigators
- Philip Leder
Bmal1lox Targeted Mutation Mice
Mice homozygous for this conditional (floxed) allele possess loxP sites flanking exon 8 of the targeted gene and are viable and fertile, with circadian behavioral rhythms indistinguishable from wildtype littermates. When bred to mice that express…
Investigators
- Charles Weitz
C3.B6-Chr3
A chromosome substitution or consomic strain is an inbred strain with one of its chromosomes replaced by the homologous chromosome of another inbred strain. The C57BL/6J and C3H/HeJ inbred strains were selected for this consomic because they differ…
DBD
- Maryanne Fenerjian
Investigators
- William Dietrich
Caspase 2 Knock Out Mice
Mice homozygous for this caspase-2 targeted mutation are viable and fertile. As the mutation deletes the QACRG active site and the caspase-2S sequence of the endogenous enzyme, this deletion was shown to inactivate both the long and short form of…
DBD
- Grant Zimmermann
Investigators
- Junying Yuan
Cd1 Knock Out Mice
Mice homozygous for the Cd1tm1Gru targeted mutation are deficient in both the Cd1d1 and Cd1d2 genes (CD1.1, CD1.2). Homozygous mutant mice lack the normal natural killer cell-like T cell subset. However, type 2 T helper cell (TH2) response is…
DBD
- Irit Ben-Chelouche
Investigators
- Michael Grusby
Cdk5lox Targeted Mutation Mice
These Cdk5 floxed mutant mice possess loxP sites flanking exons 1-5. Mice that are homozygous for this allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. When bred to mice that express Cre…
DBD
- Irit Ben-Chelouche
Investigators
- Li-Huei Tsai
Chx10-EGFP/cre,-ALPP Transgenic Mice
Mice hemizygous for the transgenic insert are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. The transgene insert contains a fusion product involving Cre recombinase and an Enhanced Green…
DBD
- Grant Zimmermann
Investigators
- Connie Cepko
Cited1-nuc-TagRFP-T Transgenic Mice
These transgenic mice express the Tag-RFPT variant of Red Fluorescent Protein under the direction of the mouse Cited1, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1, promoter. TagRFP is the optimized monomeric…
DBD
- Vivian Berlin
Investigators
- Andrew McMahon
Cldn6CIHV Targeted Mutation Mice
In this strain, the Cldn6CIHV allele replaces the entire coding region of the claudin 6 (Cldn6) locus with a CreERT2 fusion protein, an internal ribosome entry site (IRES), and a histone H2B-Venus fluorescent protein. This abolishes gene expression.…
DBD
- Vivian Berlin
Investigators
- Douglas Melton