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Ror1f/f Targeted Mutation Mice

These Ror1f/f mutant mice possess loxP sites flanking exons 3-4 of the receptor tyrosine kinase-like orphan receptor 1 (Ror1) gene. Mice that are homozygous for this allele are viable and fertile. ROR1 is a receptor for Wnt5a-mediated signaling.…

DBD

  • Irit Ben-Chelouche

Investigators

  • Michael Greenberg

Ror2f/f Targeted Mutation Mice

These Ror2f/f mutant mice possess loxP sites flanking exons 3-4 of the receptor tyrosine kinase-like orphan receptor 2 (Ror2) gene. Mice that are homozygous for this allele are viable, fertile, normal in size and do not display any gross physical or…

DBD

  • Irit Ben-Chelouche

Investigators

  • Michael Greenberg

ROSA 26Sortm1(Smo/EYFP) Transgenic Mice

When these mice are used in conjunction with a Cre recombinase-expressing strain, successful Cre-mediated excision results in the constitutive expression of the Smo/EYFP fusion gene (monitored by using EYFP-specific fluorescence protocols) and…

DBD

  • Vivian Berlin

Investigators

  • Andrew McMahon

ROSA26::FLPe Knock In Mice

Homozygous FLPeR mice are viable and fertile, with widespread expression of the FLPe variant of the Saccharomyces cerevisiae FLP1 recombinase gene driven by the Gt(ROSA)26Sor promoter. The FLPe recombinase variant exhibits enhanced thermostability…

DBD

  • Grant Zimmermann

Investigators

  • Susan Dymecki

ROSA26::FLPe knock-in Targeted Mutation

Mice homozygous for the R26Fki knock-in allele (FLPeR mice) are viable and fertile, with widespread expression of the FLPe variant of the Saccharomyces cerevisiae FLP1 recombinase gene driven by the Gt(ROSA)26Sor promoter. The FLPe recombinase…

DBD

  • Grant Zimmermann

Investigators

  • Susan Dymecki

Rosa26-rtTA::Col1a1-tetO-H2B-mCherry Targeted Mutation Mice

The Rosa26-rtTA::Col1a1-tetO-H2B-mCherry double mutant mice were generated by breeding Rosa26-rtTA mice (from Stock No. 006965) with Col1a1-tetO-H2B-mCherry mice (from Stock No. 014592). The Rosa26-rtTA targeted mutation has an optimized form of…

DBD

  • Vivian Berlin

Investigators

  • Kevin Eggan

RosaGli1Flag c/c Transgenic Mice

These RosaGli1Flag c/c mice contain a floxed-neomycin resistance (neo) cassette and polyadenylation signal, cDNA encoding a FLAG-tagged GLI-Kruppel family member (Gli1) gene, an internal ribosome entry site (IRES), and a Venus yellow fluorescent…

DBD

  • Vivian Berlin

Investigators

  • Andrew McMahon

RosaGli3TFlag c/c Transgenic Mice

These RosaGli3TFlag c/c mice contain a floxed-neomycin resistance (neo) cassette and polyadenylation signal, cDNA encoding a FLAG-tagged GLI-Kruppel family member (Gli3) repressor gene, an internal ribosome entry site (IRES), and a Venus yellow…

DBD

  • Vivian Berlin

Investigators

  • Andrew McMahon

S100b-GCE

These transgenic mice express the eGFPCreERT2 (Enhanced Green Fluorescent Protein and cre/ESR1) fusion gene under the direction of the mouse S100b, S100 protein, beta polypeptide, neural, promoter. Transgene expression is detected in chondrocytes in…

DBD

  • Vivian Berlin

Investigators

  • Andrew McMahon

Shh (EGFP/cre) Transgenic Mice

This strain expresses a fusion product involving Enhanced Green Fluorescent Protein (EGFP) and Cre recombinase from the endogenous Shh locus. EGFP and cre expression are consistent with the endogenous gene. Fluorescence is detected in the distal…

DBD

  • Grant Zimmermann

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