DBD Search
Vivian Berlin
Executive Director, HMS
Displaying: 61 - 70 of 75 Results
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RosaGli3TFlag c/c Transgenic Mice
These RosaGli3TFlag c/c mice contain a floxed-neomycin resistance (neo) cassette and polyadenylation signal, cDNA encoding a FLAG-tagged GLI-Kruppel family member (Gli3) repressor gene, an internal ribosome entry site (IRES), and a Venus yellow…
Investigators
- Andrew P. McMahon
Research Tool
FoxD1GC Transgenic Mice
Heterozygous mice are viable and fertile, normal in size and do not display any gross physical or behavioral abnormalities. The DI states that the strain is homozygous lethal. The FoxD1GC allele expresses an eGFPCre fusion protein (EGFP and cre…
Investigators
- Andrew P. McMahon
Research Tool
Wnt-1/GAL4/cre-11 Trangenic Mice
When homozygous for both co-injected transgenes, Wnt-1/GAL4/cre-11 transgenic mice are viable and fertile. Of note for Wnt-1/GAL4/cre-11 transgenic mice on the original mixed genetic background, the donating investigator (Dr. Epstein) reported that…
Investigators
- Andrew P. McMahon
Research Tool
Osr1GCE Knock In Mice
Homozygous mice die upon birth with multiple abnormalities of the heart and urogenital system (among other tissues). Heterozygous mice are viable and fertile. The Osr1eGFPCreERt2 (Osr1GCE) "knock-in" allele both abolishes Osr1 gene function and…
Investigators
- Andrew P. McMahon
Research Tool
Pdx1-CreER Transgenic Mice
Pancreatic cells are derived from Pdx1 (pancreatic and duodenal homeobox 1)-expressing progenitors throughout embryogenesis. This conditional transgenic strain expresses Cre/Esr1 from the mouse Pdx1 promoter. Cytoplasmic stores of Cre recombinase…
Investigators
- Douglas Melton
Research Tool
B6N.Sox2-Cre Transgenic Mice
These transgenic mice express Cre recombinase under the control of the mouse SRY-box containing gene 2 promoter. The transgene integrated into an intron of Edil3 (EGF-like repeats and discoidin I-like domains 3). The insertion results in a…
Investigators
- Andrew P. McMahon
Research Tool
Smo Knock Out Mice
Mice that are heterozygous for the targeted allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Homozygous null mice have an embryonic lethal phenotype, failing to develop past 9.5 days post…
Investigators
- Andrew P. McMahon
Research Tool
KRT14-cre Transgenic Mice
Mice hemizygous for the K14-Cre transgene are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. These transgenic mice express Cre recombinase under the control of the human keratin 14 promoter. Cre…
Investigators
- Andrew P. McMahon
Research Tool
Wnt7b Knock Out Mice
Mice that are heterozygous for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Homozygous mice have an embryonic lethal phenotype, failing to develop past 11.5 days post…
Investigators
- Andrew P. McMahon
Research Tool
S100b-GCE
These transgenic mice express the eGFPCreERT2 (Enhanced Green Fluorescent Protein and cre/ESR1) fusion gene under the direction of the mouse S100b, S100 protein, beta polypeptide, neural, promoter. Transgene expression is detected in chondrocytes in…
Investigators
- Andrew P. McMahon