Displaying: 21 - 30 of 36 Results

Control over deposition of nanoscale materials using structured surfaces

The ability to precisely localize and control deposition of materials at the nanoscale is extremely important for a wide variety of emerging technologies. Many unique physical properties emerge only at the nanoscale and it is very useful to be able…

Investigators

  • Joanna Aizenberg
  • Benjamin D. Hatton

Vertical silicon nanowires as a universal platform for highly efficient delivery of bioactive molecules into living cells

This platform consists of an array of surface-modified vertical silicon nanowires that have been chemically grown or etched on a wafer and to which virtually any kind of bioactive species (drug, protein, nucleic acid, nanoparticles) may be attached…

Investigators

  • Hongkun Park
  • EunGyeong Yang
  • JinSeok Lee
  • Alexander K. Shalek
  • Myung-Han Yoon
  • Jacob Robinson
  • Amy A. Sutton
  • Marsela Jorgolli

Probing a living cell through a nanotube

The hybrid nanoscale system developed by Prof. Lieber’s team provides a unique approach for recording intracellular electrical signals. The system consists of a hollow nanotube, which serves as a probe, and a Si nanowire based field-effect…

Investigators

  • Charles M. Lieber
  • Xiaojie Duan
  • Ruixuan Gao
  • Ping Xie
  • Xiaocheng Jiang

Paper-supported 3D cell culture for cell and tissue-based bioassays

In this new approach, cells are cultured in 3D on a paper scaffold by adding a hydrogel precursor, as a fluid containing suspended cells, to a paper support, allowing the cell-containing fluid to distribute through the paper by capillary wicking,…

Investigators

  • George M. Whitesides
  • Ratmir Derda
  • Anna Laromaine Sague

Improved metal complex chemical precursors for atomic layer deposition (ALD) and chemical vapor depostion (CVD) using bicyclic guanidines

A new class of metal complex precursors has been identified for use in atomic layer deposition (ALD) and chemical vapor deposition (CVD), using bicycle guanidines as ligands as opposed to acetamidines. The ALD process involves the alternating…

Investigators

  • Roy G. Gordon
  • Leonard N.J. Rodriguez

Cyborg tissue: Macroporous nanowire nanoelectronic scaffolds for synthetic tissues

This technology uses macroporous, flexible and free-standing nanowire nanoelectronic scaffolds (nanoES), and their hybrids with synthetic or natural biomaterials. 3D macroporous nanoES mimic the structure of natural tissue scaffolds. The structures…

Investigators

  • Charles M. Lieber
  • Bozhi Tian
  • Jia Liu

Investigators

  • Roy G. Gordon
  • Hoon Kim

Low-cost method for measuring the frequency content of a signal above the acquisition rate

Harvard researchers have developed a new method for determining the PSD of a signal that dramatically extends the effective detection bandwidth of current instruments. The invention circumvents previous limitations of acquisition rate and detector…

Investigators

  • Wesley Philip Wong
  • Kenneth Anders Halvorsen

Improved amide synthesis using silver as a catalyst

The Madix and Friend laboratories have developed a novel amide synthesis that uses metallic silver or silver-based alloy with oxygen adsorbed on the surface to catalyze the reaction of primary or secondary amines with alcohols or aldehydes. The…

Investigators

  • Cynthia Friend
  • Robert J. Madix
  • Ling Zhou
  • Bingjun Xu
  • Cassandra G. Freyschlag

Microfluidic arrays for multiplex detection of analyts

This invention is a microfluidic array apparatus and a method of performing multiple analyses on multiple samples simultaneously, utilizing nanoliter volumes of reagents. It has two embodiments, the first consists of N microfluidic channels, perhaps…

Investigators

  • George M. Whitesides
  • Rustem F. Ismagilov
  • Jessamine Ng Lee
  • Paul JA Kenis
  • Xingyu Jiang
  • Rosaria Ferrigno

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