Spin-Lock Induced Crossing (SLIC) pulse sequence for NMR spectroscopy and imaging

Nuclear magnetic resonance (NMR) spectroscopy is an important tool for determining the chemical structure of molecules, and it is used extensively for biomedical research and drug discovery. However, in many samples the frequency signatures of different nuclei overlap (fully or partially), making molecular identification difficult or impossible. This invention overcomes this challenge and enables higher resolution and more powerful imaging. It consists of a method of applying a sequence of radio frequency pulses to a target sample and layering molecular structure data onto the spatially-resolved images.

Intellectual Property Status: Patent(s) Pending