Upk3a-GCE Transgenic Mice

These transgenic mice express the eGFPCreERT2 (Enhanced Green Fluorescent Protein and cre/ESR1) fusion gene under the direction of the mouse Upk3a, uroplakin 3A, promoter. Transgene expression is detected in the bladder urothelium and ureters of embryos, 15.5 embryonic days of age. Tamoxifen induced Cre recombinase activity is detected in the bladder of neonatal hemizygotes. GFP fluorescence is detected in cells lining the bladder lumen from embryos, 15.5 embryonic days of age. Mice that are hemizygous for the transgene are viable, fertile, normal in size and do not display physical or behavioral abnormalities. This strain was transferred from the collection of the GenitoUrinary Development Molecular Anatomy Project (GUDMAP). The Jackson Laboratory 2024, used with permission.

Jax Stock Number: 15855