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Invention

Control over deposition of nanoscale materials using structured surfaces

The ability to precisely localize and control deposition of materials at the nanoscale is extremely important for a wide variety of emerging technologies. Many unique physical properties emerge only at the nanoscale and it is very useful to be able…

Invention

Vertical silicon nanowires as a universal platform for highly efficient delivery of bioactive molecules into living cells

This platform consists of an array of surface-modified vertical silicon nanowires that have been chemically grown or etched on a wafer and to which virtually any kind of bioactive species (drug, protein, nucleic acid, nanoparticles) may be attached…

Invention

Probing a living cell through a nanotube

The hybrid nanoscale system developed by Prof. Lieber’s team provides a unique approach for recording intracellular electrical signals. The system consists of a hollow nanotube, which serves as a probe, and a Si nanowire based field-effect…

Invention

Paper-supported 3D cell culture for cell and tissue-based bioassays

In this new approach, cells are cultured in 3D on a paper scaffold by adding a hydrogel precursor, as a fluid containing suspended cells, to a paper support, allowing the cell-containing fluid to distribute through the paper by capillary wicking,…

Invention

Improved metal complex chemical precursors for atomic layer deposition (ALD) and chemical vapor depostion (CVD) using bicyclic guanidines

A new class of metal complex precursors has been identified for use in atomic layer deposition (ALD) and chemical vapor deposition (CVD), using bicycle guanidines as ligands as opposed to acetamidines. The ALD process involves the alternating…

Invention

Cyborg tissue: Macroporous nanowire nanoelectronic scaffolds for synthetic tissues

This technology uses macroporous, flexible and free-standing nanowire nanoelectronic scaffolds (nanoES), and their hybrids with synthetic or natural biomaterials. 3D macroporous nanoES mimic the structure of natural tissue scaffolds. The structures…

Invention

Self-aligned barrier layers

Invention

Low-cost method for measuring the frequency content of a signal above the acquisition rate

Harvard researchers have developed a new method for determining the PSD of a signal that dramatically extends the effective detection bandwidth of current instruments. The invention circumvents previous limitations of acquisition rate and detector…

Invention

Improved amide synthesis using silver as a catalyst

The Madix and Friend laboratories have developed a novel amide synthesis that uses metallic silver or silver-based alloy with oxygen adsorbed on the surface to catalyze the reaction of primary or secondary amines with alcohols or aldehydes. The…