DBD Search
Irit Ben-Chelouche
Director of Business Development, Harvard Medical School
Displaying: 41 - 50 of 80 Results
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Thy1-Brainbow 1.0 Trangenic Mice
These Thy1-Brainbow 1.0 (line L) transgenic mice are viable and fertile. The mice possess multiple fluorescent protein sequences uniquely flanked with pairs of incompatible Lox sites alternated to create mutually exclusive recombination events;…
Investigators
- Jeffrey W. Lichtman
Research Tool
Cdk5lox Targeted Mutation Mice
These Cdk5 floxed mutant mice possess loxP sites flanking exons 1-5. Mice that are homozygous for this allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. When bred to mice that express Cre…
Investigators
- Li-Huei Tsai
Research Tool
Slamf2 Knock Out Mice
The Cd48 gene, also know as Slamf2 (signaling lymphocytic activation molecule 2), encodes for a lymphocyte cell surface antigen that binds CD2 and CD244 and is involved in regulation of T cell activation. These mice carry a targeted mutation for…
Investigators
- Arlene H. Sharpe
Research Tool
p26 Tg Transgenic Mice
Hemizygous transgenic mice are viable, fertile, normal in size and do not display any behavioral abnormalities. Mice homozygous for this transgene may not be viable. When these transgenic mice are bred with mice expressing the…
Investigators
- Li-Huei Tsai
Research Tool
Trpa1 Knock Out Mice
Homozygous mice are viable and fertile. The donating investigator reports a dramatic loss of fecundity after 5-6 months of age. The targeting vector contains an endoplasmic reticulum (ER) retention signal (KDEL), which is reported to sequester the…
Investigators
- David P. Corey
Research Tool
Hbva-x Targeted Mutation Mice
Mice that are homozygous for this targeted mutation have an embryonic lethal phenotype. No gene product (mRNA) is detected by Northern blot analysis of homozygous embryos. _-globin mRNA expression is also reduced in homozygous embryos. Homozygous…
Investigators
- Philip Leder
Research Tool
Thy1-Brainbow 1.1 Transgenic Mice
These Thy1-Brainbow 1.1 (line M) transgenic mice are viable and fertile. The mice possess multiple fluorescent protein sequences uniquely flanked with pairs of incompatible Lox sites alternated to create mutually exclusive recombination events;…
Investigators
- Jeffrey W. Lichtman
Research Tool
Daxxlox Targeted Mutation Mice
These mice possess loxP sites on either side of exon II (also called exon 3, when the first non-coding exon is included in the numbering scheme) of the targeted gene. Mice that are homozygous for this allele are viable and fertile. Sequence analysis…
Investigators
- Philip Leder
Research Tool
Lsd1fl Targeted Mutation Mice
These LSD1fl/fl mice possess loxP sites flanking exons 5-6 of the lysine (K)-specific demethylase 1A (Kdm1a) gene. LSD1 demethylates histone H3 on Lys4 or Lys9 (H3K4/K9) and represses hematopoietic stem and progenitor cell (HSPC) gene expression…
Research Tool
p35 Knock Out Mice
At birth, mice homozygous for this targeted allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Cdk5r protein product is not immunodetectable in homozygote whole-brain lysates. Histological…
Investigators
- Li-Huei Tsai