DBD Search
Vivian Berlin
Executive Director, HMS
Displaying: 51 - 60 of 75 Results
Research Tool
Disp1_2C Transgenic Mice
These mice possess loxP sites on either side of exon 2 of the targeted gene. Mice that are homozygous for this allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. When used in conjunction…
Investigators
- Andrew P. McMahon
Research Tool
Upk3a-GCE Transgenic Mice
These transgenic mice express the eGFPCreERT2 (Enhanced Green Fluorescent Protein and cre/ESR1) fusion gene under the direction of the mouse Upk3a, uroplakin 3A, promoter. Transgene expression is detected in the bladder urothelium and ureters of…
Investigators
- Andrew P. McMahon
Research Tool
Meox1-nucTagRFP-T-IRES-CE Transgenic Mice
These Meox1-nucTagRFP-T-IRES-CE mutant mice have a tamoxifen inducible Cre-mediated recombination system and express the nuclear-localized Tag-RFPT variant of Red Fluorescent Protein under the direction of the mouse Meox1, mesenchyme homeobox 1,…
Investigators
- Andrew P. McMahon
Research Tool
B6(D2)-Tg(CAG-Brainbow1.0)2 Transgenic Mice
These transgenic mice carry the Brainbow 1.0 cassette, incorporating dTomato, mCerulean, and EYFP, driven by the broadly-expressed CAG (CMV-chicken beta actin) promoter. These fluorescent markers are useful in tracing cell lineage. This strain, line…
Investigators
- Kevin Carl Eggan
Research Tool
Shh Knock Out Mice
Mice homozygous for the Shhtm1Amc targeted mutation display early defects in the establishment and maintenance of midline structures. These defects result from the critical role the Sonic hedgehog (Shh) gene plays in the patterning of vertebrate…
Investigators
- Andrew P. McMahon
Research Tool
FoxD1GC Transgenic Mice
Heterozygous mice are viable and fertile, normal in size and do not display any gross physical or behavioral abnormalities. The DI states that the strain is homozygous lethal. The FoxD1GC allele expresses an eGFPCre fusion protein (EGFP and cre…
Investigators
- Andrew P. McMahon
Research Tool
Wnt-1/GAL4/cre-11 Trangenic Mice
When homozygous for both co-injected transgenes, Wnt-1/GAL4/cre-11 transgenic mice are viable and fertile. Of note for Wnt-1/GAL4/cre-11 transgenic mice on the original mixed genetic background, the donating investigator (Dr. Epstein) reported that…
Investigators
- Andrew P. McMahon
Research Tool
Ngn3/CreER Trangenic Mice
These transgenic mice have a tamoxifen inducible Cre-mediated recombination system driven by the mouse neurogenin 3, Neurog3, promoter. The transgene insert contains a fusion product involving Cre recombinase and a mutant form of the mouse estrogen…
Investigators
- Douglas Melton
Research Tool
B6(D2)-Tg(CAG-Brainbow1.0)3 Transgenic Mice
These transgenic mice carry the Brainbow 1.0 cassette, incorporating dTomato, mCerulean, and EYFP, driven by the broadly-expressed CAG (CMV-chicken beta actin) promoter. These fluorescent markers are useful in tracing cell lineage. This strain, line…
Investigators
- Kevin Carl Eggan
Research Tool
Shh Targeted Mutation Mice
Mice that are homozygous for the Shhtm2Amc targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. This conditional mutant contains two loxP sites flanking exon 2 of the targeted…
Investigators
- Andrew P. McMahon