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Preventing Stress-Induced Greying of Hair

Loss of hair pigmentation has long been associated with stress; however, stress-related changes at the level of the somatic cell have only recently been elucidated. The hair follicle consists of two stem cell populations: epithelial-derived hair…

Investigators

  • Ya-Chieh Hsu
  • Bing Zhang

Guiding electrons in graphene with a carbon nanotube

Researchers from Philip Kim’s lab at Harvard have developed a device that creates a mono-mode electronic waveguide in graphene using a carbon nanotube as a gate. The nanotube and graphene are separated by nanometers and are coupled such that they…

Investigators

  • Philip Kim
  • Austin Cheng
  • Jean-Damien Pillet

Wearables to Monitor Strength Training

The ability to track and monitor one’s own exercise routine is fundamental to assessing overall fitness and supporting a healthy lifestyle. While conventional fitness wearables typically capture metrics relating to cardio output, researchers in the…

Investigators

  • Conor Walsh

Continuous Evolution (PACE) of Botulinum Neurotoxins with Reprogrammed Substrate Specificity for Intracellular Protease Therapy

Biomacromolecule-based therapies are of keen interest to the pharmaceutical industry because macromolecules engage in highly specific interactions in biological systems compared to traditional small molecules. Despite their success, macromolecular…

Investigators

  • David Liu

Nanophotonic quantum memory for quantum key distribution

Quantum networks have the potential to unlock significant advancements in secure communications. Such networks require nodes which perform quantum processing on a small register of interconnected qubits with long coherence times. Harvard reseachers…

Investigators

  • Mikhail Lukin
  • Marko Loncar
  • Denis Sukachev
  • Christian Nguyen
  • Bartholomeus Machielse
  • David Levonian
  • Ralf Riedinger
  • Mihir Bhaskar

Red Blood Cell-Hitchhiking for Targeted Drug Delivery

Drug delivery utilizing nanocarriers (NCs) as a targeted approach has been actively pursued; however, even with the use of different affinity moieties such as antibodies to improve targeting and reduce off-target toxicity, NCs are predominately…

Investigators

  • Samir Mitragotri

Novel Biochemical and Computational Approaches to Increase Mass Spectrometry Sensitivity

Mass spectrometry (MS) has become the leading protein identification technique. Current mass spectrometry methods rely on tandem MS/MS detection, where a prepared peptide digestion sample is injected into the mass spectrometer and analyzed by its…

Investigators

  • Marc Kirschner
  • Mingjie Dai

New Raman Microscopy Technique Accelerates Digital Pathology

Current methods for pathological diagnosis of diseases require laborious and costly sample processing steps and provide inherently qualitative information. Moreover, batch to batch variations in staining intensity results in highly variable images,…

Investigators

  • Marc Kirschner
  • Seungeun Oh

DNA Destruction Through Novel and Adaptable Enzymes

Bacteria in mixed populations compete for resources and have several strategies on surviving and dominating other bacterial species. One method employs the injection of lethal effectors into adjacent cells. These effectors can disrupt cell membranes…

Investigators

  • Karine Gibbs

Inhibiting Microbial Metabolism of Levodopa to Increase Availability in the CNS

Parkinson’s disease (PD) impacts 10 million people globally, with 60,000 Americans newly diagnosed every year. Levodopa remains the gold standard treatment for PD, despite limitations including side effects and peripheral metabolism. Current…

Investigators

  • Emily Balskus

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