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Direct processing of saltwater for renewable energy storage
Technological advances have created an abundance of renewable energy sources (wind and solar), however, storing energy at scale is an essential part of transitioning to renewables and remains a critical challenge. The Nocera lab has developed a…
Investigators
- Daniel Nocera
- Samuel Veroneau
Preventing Stress-Induced Greying of Hair
Loss of hair pigmentation has long been associated with stress; however, stress-related changes at the level of the somatic cell have only recently been elucidated. The hair follicle consists of two stem cell populations: epithelial-derived hair…
Investigators
- Ya-Chieh Hsu
- Bing Zhang
Wearables to Monitor Strength Training
The ability to track and monitor one’s own exercise routine is fundamental to assessing overall fitness and supporting a healthy lifestyle. While conventional fitness wearables typically capture metrics relating to cardio output, researchers in the…
Investigators
- Conor Walsh
Continuous Evolution (PACE) of Botulinum Neurotoxins with Reprogrammed Substrate Specificity for Intracellular Protease Therapy
Biomacromolecule-based therapies are of keen interest to the pharmaceutical industry because macromolecules engage in highly specific interactions in biological systems compared to traditional small molecules. Despite their success, macromolecular…
Investigators
- David Liu
Nanophotonic quantum memory for quantum key distribution
Quantum networks have the potential to unlock significant advancements in secure communications. Such networks require nodes which perform quantum processing on a small register of interconnected qubits with long coherence times. Harvard researchers…
Investigators
- Mikhail Lukin
- Marko Loncar
- Denis Sukachev
- Christian Nguyen
- Bartholomeus Machielse
- David Levonian
- Ralf Riedinger
- Mihir Bhaskar
Novel Biochemical and Computational Approaches to Increase Mass Spectrometry Sensitivity
Mass spectrometry (MS) has become the leading protein identification technique. Current mass spectrometry methods rely on tandem MS/MS detection, where a prepared peptide digestion sample is injected into the mass spectrometer and analyzed by its…
Investigators
- Marc Kirschner
- Mingjie Dai
New Raman Microscopy Technique Accelerates Digital Pathology
Current methods for pathological diagnosis of diseases require laborious and costly sample processing steps and provide inherently qualitative information. Moreover, batch to batch variations in staining intensity results in highly variable images,…
Investigators
- Marc Kirschner
- Seungeun Oh
Inhibiting Microbial Metabolism of Levodopa to Increase Availability in the CNS
Parkinson’s disease (PD) impacts 10 million people globally, with 60,000 Americans newly diagnosed every year. Levodopa remains the gold standard treatment for PD, despite limitations including side effects and peripheral metabolism. Current…
Investigators
- Emily Balskus
Reproducible Individual Brain Organoids
The human brain is a highly complex organ comprised of a variety of cell types and that are largely generated during embryonic development. While this process is invariable in vivo, it is unclear if this can be recapitulated outside of the embryo.…
Investigators
- Paola Arlotta
Cyborg organoids with fully integrated nanoelectronics
Researchers from the Liu lab at Harvard have grown organoids with fully integrated sensors that grow with the developing cells, giving them the unique ability to study the early stages of organ development. Organoids are 3D clusters of cells that…
Investigators
- Jia Liu
- Kewang Nan
- Qiang Li