Displaying: 1-10 of 16 Results
Differentiated CD8+ effector T cells mediate long-term immunity and protection against infectious diseases and cancer. Naive T cells are…
Investigators:
Arlene Sharpe
Nicholas Haining
Despite decades of adjuvant research, only a handful of adjuvants have been approved in seven major global markets and only two (Alum and…
Investigators:
Ulrich von Andrian
Matteo Iannacone
Elena Tonti
Elliott Moseman
Homozygous Cd1tm1Gru knock-out mice (C.129S2-Cd1tm1Gru/J, also known as CD1-) were developed by Dr. Michael J. Grusby at Harvard…
Investigators:
Michael Grusby
DESCRIPTION Template-directed synthesis of modified DNA sequences can provide a rich source of material for generating new therapies…
Investigators:
David Liu
Homozygous IKKepsilon (inhibitor of kappaB kinase epsilon) mutant mice are used as animal models for influenza virus infection. Homozygous…
Investigators:
Thomas Maniatis
Benjamin tenOever
Professors Diane Mathis and Christophe Benoist at Harvard Medical School, together with other world-renowned immunologists and computational…
Investigators:
Diane Mathis
Christophe Benoist
Researchers in the lab of James Chou have engineered a new way to display membrane proteins to enhance vaccine immunogenicity using…
Investigators:
James Chou
Reactive oxygen species (ROS) and oxidative stress are believed to cause and/or aggravate several diseases, including inflammatory diseases…
Investigators:
Wendy Garrett
To study the biological role of migration inhibitory factor (MIF), a pleiotropic cytokine, we generated a mouse strain lacking MIF by gene…
Investigators:
John David
Marcelo Bozza
Craig Gerard
Researchers in the lab of Ulrich von Andrian have discovered a novel adjuvanting behavior of a clinically approved and well-tolerated class…
Investigators:
Ulrich von Andrian