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AlignAce motif searching software

Developed by genomics researchers at Harvard Medical School, AlignAce employs an algorithm that scans non-coding nucleic acid sequences at high resolution for motifs that occur with non-random frequency. This algorithm is built into a multi-level sequence analysis program that highlights gene-specific regulatory elements for further analysis.

AlignAce offers both efficiency and convenience. Its high signal-to-noise ratio preferentially reduces false positives in the program output, while iterative masking uncovers multiple, distinct sequence motifs within a single data set. In gene expression studies, Alignace easily highlights potential gene regulatory elements and sets of co-regulated genes. Nucleic acid sequences identified by AlignAce may be used as drug targets or, alternatively, as bait to isolate gene-specific trans-regulatory proteins for use as drugs or drug targets.

Intellectual Property Status: Patent(s) Pending

Applications

Genomics and gene regulatory analyses for basic research or drug development.

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