Animal model of diabetes and obesity

Mice with the JNK 1 and JNK2 genes knocked out were crossed with the obese mouse line (ob/ob) to create a mouse model of diabetes and obesity. These mice exhibit many of the hallmark metabolic pertubations characteristic in diabetes and obesity.


These mice are a research tool that can be used to screen therapeutic compounds for efficacy in diabetes and obesity.

Intellectual Property Status: Patent(s) Pending