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Displaying: 11 - 20 of 103 Results
Glp1r-ires-Cre (Glp1r-ires-Cre knock-in mice)
Glp1r (Glucagon-Like Peptide 1 Receptor) -ires-Cre knock-in mice were developed in Dr. Stephen Liberles lab at Harvard Medical School. IRES and Cre sequence were inserted after the gene Glp1r, thus the mouse strain expresses Cre recombinase in cells…
DBD
- Grant Zimmermann
Investigators
- Stephen Liberles
Gpr65-ires-Cre (Gpr65-ires-Cre knock-in mice)
Gpr65 (G Protein-Coupled Receptor 65) -ires-Cre knock-in mice were developed by Dr. Stephen Liberles and members of his lab at Harvard Medical School. In these mice, expression of Cre recombinase is controlled by Gpr65 promoter in Gpr65-positive…
DBD
- Grant Zimmermann
Investigators
- Stephen Liberles
Hba-a1 knockout mice
Homozygous Hba-a1 (hemoglobin alpha, adult chain 1) knockout mice (129S-Hba-a1tm1Led/J) were developed by HHMI Investigator Dr. Philip Leder and his lab at Harvard Medical School. While the mice are viable and fertile, they develop anemia with…
DBD
- Irit Ben-Chelouche
Investigators
- Philip Leder
CD1- mice developed in the laboratory of Dr. Michael Grusby
Homozygous Cd1tm1Gru knock-out mice (C.129S2-Cd1tm1Gru/J, also known as CD1-) were developed by Dr. Michael J. Grusby at Harvard University. The mutant mice are deficient in both the Cd1.1 and Cd1.2 genes, and lack the normal natural killer…
DBD
- Grant Zimmermann
Investigators
- Michael Grusby
B6.Cg-Shhtm1(EGFP/cre)Cjt/J mice developed in the laboratory of Dr. Clifford Tabin
This mouse stain, also known as Shhgfpcre was originally described in Cell in 2004. The mice express GFP in all cell expressing Shh, and specifically, in the distal posterior region of the limb buds of embryos aged embryonic day 10 to 12. Mice…
DBD
- Grant Zimmermann
Investigators
- Clifford Tabin
ROSA26 FLPeR mice developed in the laboratory of Dr. Susan Dymecki
Homozygous FLPe knock-in mice (B6N.129S4-Gt(ROSA)26Sortm1(FLP1)Dym/J, also known as ROSA26::FLPe knock in) were developed by Dr. Susan Dymecki using ROSA26 segments provided by Dr. Phillippe Soriano. The mouse strain carries the FLPe knock-in allele…
DBD
- Grant Zimmermann
Investigators
- Susan Dymecki
“TRUC mice” Tbx21-/-.Rag2-/- (BALB/c) mice developed by Dr. Laurie Glimcher
Homozygous T-bet-/- × RAG2-/- deficient mice were created in the laboratory of Dr. Glimcher at Harvard University. These mice develop a spontaneous jevenille ulcerative colitis resulting from a pro-inflammatory response to the commensal microbiota…
DBD
- Grant Zimmermann
CDK5R1/p25 transgenic mice developed in the laboratory of Dr. Li-Huei Tsai
Hemizygous CDK5R1 transgenic mice (C57BL/6-Tg(tetO-CDK5R1/GFP)337Lht/J, also known as p25 Tg) were developed in the laboratory of a former HHMI investigator Dr. Li-Huei Tsai at Harvard University. The mice express CDK5R1/GFP fusion protein under the…
DBD
- Grant Zimmermann
Trpa1 conditional knockout mice
The mouse strain 129S-Trpa1tm2Kykw/J was developed by Kelvin Kwan in the laboratory of HHMI Investigator David Corey at Harvard Medical School. Trpa1 conditional knockout animals were generated by flanking the exons that code for the pore domain of…
DBD
- Irit Ben-Chelouche
Investigators
- Kelvin Kwan
- David Corey
TRPA1 knockout mice developed in the laboratory of Professor David Corey
Homozygous Transient Receptor Potential Cation Channel Subfamily A Member 1 (TRPA1) mutant mice (B6;129P-Trpa1tm1Kykw/J, also known as Trpa1 KO) were developed by HHMI Investigator David Corey at Harvard Medical School. They exhibit abnormal…
DBD
- Irit Ben-Chelouche
Investigators
- David Corey